Monday, February 9, 2009

Optivar


Generic Name: azelastine (Ophthalmic route)

a-ZEL-as-teen

Commonly used brand name(s)

In the U.S.


  • Optivar

Available Dosage Forms:


  • Solution

Therapeutic Class: Ophthalmologic Agent


Pharmacologic Class: Antihistamine


Uses For Optivar


Azelastine ophthalmic (eye) solution is used to treat itching of the eye caused by a condition known as allergic conjunctivitis. It works by preventing the effects of certain inflammatory substances, which are produced by cells in your eyes and sometimes cause allergic reactions.


This medicine is available only with your doctor's prescription.


Before Using Optivar


In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:


Allergies


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.


Pediatric


Studies on this medicine have been done only in adult patients, and there is no specific information comparing use of azelastine in children under the age of 3 years with use in other age groups.


Geriatric


This medicine has been tested and has not been shown to cause different side effects or problems in older people than it does in younger adults.


Pregnancy








Pregnancy CategoryExplanation
All TrimestersCAnimal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding


There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.


Interactions with Medicines


Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.


Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.


  • Cimetidine

Interactions with Food/Tobacco/Alcohol


Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.


Proper Use of Optivar


Do not wear contact lenses if your eyes are red. If your eyes are not red, contact lenses should be removed before you use this medicine. Also, you should wait at least 10 minutes after using this medicine before putting the contact lenses back in.


To use:


  • The bottle is only partially full to provide proper drop control.

  • First, wash your hands. Tilt the head back and, pressing your finger gently on the skin just beneath the lower eyelid, pull the lower eyelid away from the eye to make a space. Drop the medicine into this space. Let go of the eyelid and gently close the eyes. Do not blink. Keep the eyes closed for 1 to 2 minutes to allow the medicine to be absorbed by the eye.

  • If you think you did not get the drop of medicine into your eye properly, use another drop.

  • Immediately after using the eye drops, wash your hands to remove any medicine that may be on them.

To keep the medicine as germ-free as possible, do not touch the applicator tip to any surface (including the eye). Also, keep the container tightly closed. Serious damage to the eye and possible loss of vision may result from using contaminated eye drops.


Dosing


The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.


The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.


  • For ophthalmic dosage form (eye drops):
    • For eye allergy:
      • Adults and children 3 years of age and older—Use one drop in the affected eye twice a day.

      • Children younger than 3 years of age—Use and dose must be determined by your doctor.



Missed Dose


If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.


Storage


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.


Keep out of the reach of children.


Do not keep outdated medicine or medicine no longer needed.


Ask your healthcare professional how you should dispose of any medicine you do not use.


Keep bottle in an upright position.


Precautions While Using Optivar


If your symptoms do not improve within a few days or if they become worse, check with your doctor.


Optivar Side Effects


Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.


Check with your doctor immediately if any of the following side effects occur:


Less common
  • Cough

  • difficulty breathing

  • noisy breathing

  • shortness of breath

  • tightness in chest

  • wheezing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:


More common
  • Bitter taste in mouth

  • headaches

  • temporary eye burning or stinging

Less common
  • Burning, dry or itching eyes

  • blurred vision, temporary

  • chills

  • diarrhea

  • eye discharge or excessive tearing

  • fever

  • general feeling of discomfort or illness

  • hoarseness or other voice changes

  • itching skin

  • joint pain

  • loss of appetite

  • muscle aches and pains

  • nausea

  • redness, pain, swelling of eye, eyelid, or inner lining of eyelid

  • runny nose

  • shivering

  • sneezing

  • sore throat

  • stuffy nose

  • sweating

  • tender, swollen glands in neck

  • trouble in swallowing

  • trouble sleeping

  • unusual tiredness or weakness

  • vomiting

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.


Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Optivar side effects (in more detail)



The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.


The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.


More Optivar resources


  • Optivar Side Effects (in more detail)
  • Optivar Use in Pregnancy & Breastfeeding
  • Optivar Drug Interactions
  • Optivar Support Group
  • 1 Review for Optivar - Add your own review/rating


  • Optivar Prescribing Information (FDA)

  • Optivar Concise Consumer Information (Cerner Multum)

  • Optivar Drops MedFacts Consumer Leaflet (Wolters Kluwer)



Compare Optivar with other medications


  • Conjunctivitis, Allergic

Sunday, February 8, 2009

Bendroflumethiazide/Nadolol


Pronunciation: BEN-droe-FLOO-me-THYE-a-zide/NAY-doe-lol
Generic Name: Bendroflumethiazide/Nadolol
Brand Name: Corzide

Do not suddenly stop taking Bendroflumethiazide/Nadolol. Sharp chest pain, irregular heartbeat, and sometimes heart attack may occur if you suddenly stop Bendroflumethiazide/Nadolol. The risk may be greater if you have certain types of heart disease. Your doctor should slowly lower your dose over several weeks if you need to stop taking it. This should be done even if you only take Bendroflumethiazide/Nadolol for high blood pressure. Heart disease is common and you may not know you have it. Limit physical activity while you are lowering your dose. If new or worsened chest pain or other heart problems occur, contact your doctor right away. You may need to start taking Bendroflumethiazide/Nadolol again.





Bendroflumethiazide/Nadolol is used for:

Treating high blood pressure.


Bendroflumethiazide/Nadolol is a beta-blocker and diuretic combination. It works by decreasing the force and slowing down the heartbeat, helping the heart beat more regularly and reducing the amount of work the heart has to do. It also increases the elimination of excess fluid, which helps to decrease blood pressure.


Do NOT use Bendroflumethiazide/Nadolol if:


  • you are allergic to any ingredient in Bendroflumethiazide/Nadolol or to sulfonamide medicines (eg, glyburide, probenecid, sulfamethoxazole)

  • you have uncontrolled heart failure or a very slow and irregular heartbeat (eg, heart block)

  • you are unable to urinate

  • you have a history of asthma

  • you are taking dofetilide or mibefradil

Contact your doctor or health care provider right away if any of these apply to you.



Before using Bendroflumethiazide/Nadolol:


Some medical conditions may interact with Bendroflumethiazide/Nadolol. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have bronchitis, lung disease (eg, chronic obstructive pulmonary disease [COPD]), diabetes, gout, an overactive thyroid, low blood levels of potassium or sodium, heart problems (eg, congestive heart failure[CHF]), blood vessel problems, pheochromocytoma, lupus, liver disease, or kidney problems

  • if you are having surgery or receiving anesthesia

Some MEDICINES MAY INTERACT with Bendroflumethiazide/Nadolol. Tell your health care provider if you are taking any other medicines, especially any of the following:


  • Dofetilide or mibefradil because the risk of serious heart side effects may be increased

  • Many prescription and nonprescription medicines (eg, used for infections, inflammation, aches and pains, high blood pressure, heart problems, irregular heartbeat, diabetes, depression, mental or mood problems, immune system suppression, allergic reactions, asthma, high cholesterol, seizures), multivitamin products, and herbal or dietary supplements (eg, herbal teas, garlic, ginseng, ginkgo, St. John's wort) may interact with Bendroflumethiazide/Nadolol, increasing the risk of side effects

This may not be a complete list of all interactions that may occur. Ask your health care provider if Bendroflumethiazide/Nadolol may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Bendroflumethiazide/Nadolol:


Use Bendroflumethiazide/Nadolol as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Take Bendroflumethiazide/Nadolol by mouth with or without food.

  • Bendroflumethiazide/Nadolol may increase the amount of urine or cause you to urinate more often when you first start taking it. To keep this from disturbing your sleep, try to take your dose before 6 pm.

  • If you miss a dose of Bendroflumethiazide/Nadolol, take the missed dose if you remember the same day. Skip the missed dose if you do not remember the same day. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Bendroflumethiazide/Nadolol.



Important safety information:


  • Bendroflumethiazide/Nadolol may cause dizziness or lightheadedness. These effects may be worse if you take it with alcohol or certain medicines. Use Bendroflumethiazide/Nadolol with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.

  • Bendroflumethiazide/Nadolol may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.

  • Patients who take medicine for high blood pressure often feel tired or run down for a few weeks after starting treatment. Be sure to take your medicine even if you may not feel "normal." Tell your doctor if you develop any new symptoms.

  • Bendroflumethiazide/Nadolol may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Bendroflumethiazide/Nadolol. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.

  • Tell your doctor or dentist that you take Bendroflumethiazide/Nadolol before you receive any medical or dental care, emergency care, or surgery.

  • If you have high blood pressure, do not use nonprescription products that contain stimulants. These products may include diet pills or cold medicines. Contact your doctor if you have any questions or concerns.

  • Diabetes patients - Bendroflumethiazide/Nadolol may hide signs of low blood sugar, such as a rapid heartbeat. Be sure to watch for other signs of low blood sugar. Low blood sugar may make you anxious, sweaty, weak, dizzy, drowsy, or faint. It may also make your vision change; give you a headache, chills, or tremors; or make you more hungry. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.

  • Lab tests, including blood pressure and heart rate, may be performed while you use Bendroflumethiazide/Nadolol. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.

  • Bendroflumethiazide/Nadolol should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.

  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Bendroflumethiazide/Nadolol while you are pregnant. Bendroflumethiazide/Nadolol is found in breast milk. Do not breast feed while taking Bendroflumethiazide/Nadolol.


Possible side effects of Bendroflumethiazide/Nadolol:


All medicines may cause side effects, but many people have no, or minor side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Dizziness; lightheadedness; tiredness.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest pain; irregular heartbeat; muscle pain or weakness; swelling of ankles or feet; unusual thirst or fatigue; unusually slow or irregular heartbeat.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Bendroflumethiazide/Nadolol side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include coughing; dizziness; drowsiness; fainting; loss of consciousness; low blood pressure; muscular weakness; nausea; seizures; slow heart rate; trouble breathing; upset stomach; vomiting; weakness.


Proper storage of Bendroflumethiazide/Nadolol:

Store Bendroflumethiazide/Nadolol at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Bendroflumethiazide/Nadolol out of the reach of children and away from pets.


General information:


  • If you have any questions about Bendroflumethiazide/Nadolol, please talk with your doctor, pharmacist, or other health care provider.

  • Bendroflumethiazide/Nadolol is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Bendroflumethiazide/Nadolol. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Bendroflumethiazide/Nadolol resources


  • Bendroflumethiazide/Nadolol Side Effects (in more detail)
  • Bendroflumethiazide/Nadolol Use in Pregnancy & Breastfeeding
  • Drug Images
  • Bendroflumethiazide/Nadolol Drug Interactions
  • Bendroflumethiazide/Nadolol Support Group
  • 0 Reviews for Bendroflumethiazide/Nadolol - Add your own review/rating


Compare Bendroflumethiazide/Nadolol with other medications


  • High Blood Pressure

Friday, February 6, 2009

Pilsicainide Hydrochloride




Pilsicainide Hydrochloride may be available in the countries listed below.


Ingredient matches for Pilsicainide Hydrochloride



Pilsicainide

Pilsicainide Hydrochloride (JAN) is also known as Pilsicainide (Rec.INN)

International Drug Name Search

Glossary

JANJapanese Accepted Name
Rec.INNRecommended International Nonproprietary Name (World Health Organization)

Click for further information on drug naming conventions and International Nonproprietary Names.